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This test consists of 5 short answer questions, 10 short essay questions, and 1 (of 3) essay topics.

Short Answer Questions

1. ________________ such as Doll and Hill, argued that exogenous chemicals caused cancer, although they could not offer a mechanistic explanation for their theory or results.

2. It was ________ years later when Einar Gustafson returned to Children's Hospital to a full fanfare.

3. Rather than initiating his studies with cancer in its full-blown form, Auerbach has tried to understand what?

4. During that time period, ________________ were often employed as assistants to chimney sweeps, often with fatal results.

5. Genes could be shuffled from one _______________ to another.

Short Essay Questions

1. Who was George Papanicolaou? How was his work important?

2. What are the similarities between AIDS and cancer? Is this important? Why or why not?

3. How did the tide begin to turn regarding Americans' view smoking?

4. What was the oncomouse? Was this successful? Why or why not?

5. What is the role of a clinician? What type of people are suited for this work?

6. What is the significance of the SRC gene?

7. Mukherjee discusses the successes of others in this story. Why does he credit the survival of patients to the work of those in the 1950s and 1960s?

8. Why was Phyllis Clauson at first not believed? Is this surprising? Why or why not?

9. How did the discovery of scrotal cancer help children?

10. What is Genentech? How is this company important?

Essay Topics

Write an essay for ONE of the following topics:

Essay Topic 1

Four and five drug combinations were tested with success.

Part 1) How did researchers begin to test combinations of four and five drugs? How did many of these combinations affect patients? How did these studies lead to success?

Part 2) How did these successes affect cancer patients? How did these studies also lead to the idea of the "smiling oncologist?" How did this type of doctor affect the mindset of a patient?

Part 3) Is there a need for such an oncologist? Is that type of attitude towards cancer necessary? Why or why not?

Essay Topic 2

Cancer is not the only disease discussed in this book.

Part 1) What are two other diseases discussed in this book? Describe these two diseases. What is the purpose of having these diseases discussed in this book?

Part 2) How do these diseases compare to cancer? Which disease do you find to be the most threatening to the American people? Why?

Part 3) What similarities can be found among various diseases including all that are discussed in this book? How is this important?

Essay Topic 3

Farber created a society to raise funds for cancer research.

Part 1) Describe the work of this society. Who was involved? How did cancer research benefit from this society? What events led to changes in the work of this society?

Part 2) What other organizations are discussed in this book? How have they been important to the study of various diseases? At what times have these various organizations worked together? How did they benefit from these collaborations?

Part 3) If you were to join an organization, which one would you join? Why would you join this organization? In which ways could you help this organization raise funds?

(see the answer keys)

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