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This test consists of 15 multiple choice questions and 5 short answer questions.

Multiple Choice Questions

1. In 1976, a company named _____________ (Genetic Engineering Technology) was formed in San Francisco.
(a) Genetic Entech.
(b) Genenology.
(c) Gengology.
(d) Genentech.

2. _____________. of the seven people in Mukherjee's group continued at the clinic.
(a) Three.
(b) Six.
(c) Five.
(d) Four.

3. The ____________________ refers to something that moves incessantly but never gets anywhere.
(a) Red Queen Syndrome.
(b) Queen Bee Syndrome.
(c) Queen of Hearts Syndrome.
(d) Black Queen Syndrome.

4. How was this letter first seen?
(a) As a surprise.
(b) As a hoax.
(c) As a wonderful find.
(d) As a nuisance.

5. The trend also raised questions regarding what?
(a) The hazardous work done by the poor.
(b) The activities of these wealthy men.
(c) The secret lives of chimney sweeps.
(d) The amount of soot that the chimney sweeps carried home with them under the surface of their skin.

6. ________________ such as Doll and Hill, argued that exogenous chemicals caused cancer, although they could not offer a mechanistic explanation for their theory or results.
(a) Dermologists.
(b) Epidemiologists.
(c) Dermatologists.
(d) Epidermologists.

7. The gene, the SRC gene, is also known as the sarc, short for what?
(a) Sarcophagus.
(b) Sarcomere.
(c) Sarcoidosis.
(d) Sarcoma.

8. Scientists begin to analyze genes that were altered in mutant viruses and attempted to isolate what?
(a) The mutant virus.
(b) The DNA of the virus.
(c) The gene in the virus.
(d) The gene of the healthy cell.

9. It was determined that a DNA copy of virus' genes could do what?
(a) Replace a cell's genes.
(b) Attach themselves to a cell's genes.
(c) Destroy a cell's genes.
(d) Trick scientists into believing it was a healthy cell.

10. In 1870, the per capita consumption in America was ________________ per year.
(a) Less than one cigarette.
(b) Five cigarettes.
(c) One cigarette.
(d) Ten cigarettes.

11. In 1963, three men visited Oscar Auerbach. Why?
(a) He was the CEO of a major cigarette company.
(b) He was a very wealthy entrepreneur who could financially back cancer studies.
(c) He was the head of oncology at Johns Hopkins.
(d) He was one of the foremost pathologists and a top choice when choosing a scientist that may be able to find the cause of lung cancer.

12. Geneticists needed to learn what?
(a) To "see" the gene in a new way.
(b) To "track" the gene in a new way.
(c) To "find" the gene.
(d) To "hunt" the virus' gene.

13. The ____________ theory developed by Varmus and Bishop provided the first comprehensive theory of carcinogenesis.
(a) Cancergene.
(b) Sarcogene.
(c) Oncogene.
(d) Carcinogene.

14. By 1993, Slamon's early phase clinical trials had become a hot topic among ____________ cancer patients.
(a) Breast.
(b) Cervical.
(c) Testicular.
(d) Brain.

15. What question arose from the study of these two genes?
(a) What other types of genes can cause cancer?
(b) If two of these types of genes were not sufficient to create cancer, how many would it take?
(c) What are other causes of cancer?
(d) Why do people still get cancer?

Short Answer Questions

1. In 1961 the American Cancer Society, the American Heart Association and the __________________________ wrote a letter to President John F. Kennedy, asking for help in fighting cancer.

2. The mouse embodied what?

3. Mukherjee discusses the links between what?

4. One of the most difficult forms of cancer to treat is what?

5. During that time period, ________________ were often employed as assistants to chimney sweeps, often with fatal results.

(see the answer keys)

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