How is the connection between art and science demonstrated in Leonardo da Vinci's work?

Students should use a minimum of three examples to demonstrate how the arts and sciences come together in the work of Leonardo da Vinci, highlighting the artist's likely belief that there is no distinction between the two. Examples may include the influence of anatomical studies on his paintings, his use of mechanical inventions for theatrical performance, or his study of optics on the nature of light and shadow in painting.

How does Walter Isaacson define the nature of Leonardo's genius?

Students should be able to identity and discuss a minimum of three characters traits which Leonardo exhibited and that Isaacson identifies as markers of his genius. Examples may include his interdisciplinary mind, his power of observation, his insatiable curiosity, or his emphasis on experiential learning.

Explain what Isaacson means when he discusses the microcosm/macrocosm in Leonardo's work.