What does the apple symbolize in this story?

Compare the couples Sam and Jane with Hadley and Rebecca and how their age differences affected their relationships.

What effect does the author achieve by using five points of view in telling this story? Describe how it works well and how it works against the storytelling experience from the reader's point of view.

How does Picoult create suspense through the structure of the novel?

Of all the characters in this story, which ones would you like and which ones do you dislike? Explain using examples from the book.

Describe the approach Dr. Oliver Jones uses to find his family. What skills and methods does he use and which ones prove successful?

Discuss the theme of communication that flows through the story.

Using two characters, describe their coming of age in the course of the novel.

Describe...