Birmingham

Birmingham, Alabama is where the first family, the Jacobis, are murdered.

Atlanta

Atlanta, Georgia is where the second family, the Leedses, are murdered.

Washington, DC

Washington, DC is where FBI headquarters is located. Graham spends much of his time here, working with the various forensics people while he is searching for the Tooth Fairy.

Marathon, Florida

Marathon, Florida is where Graham is living since leaving his job as a forensics expert with the FBI. This is also where Lecter sends Dolarhyde to kill Graham.

St. Louis, Missouri

St. Louis, Missouri is where Dolarhyde works, and where Gateway Film Laboratory is located.

Chicago, Illinois

Chicago, Illinois is where Freddie Lounds lives and works, and where The National Tattler is located.

The Tooth Fairy

Tooth Fairy is the nickname given to the killer by the press after it is released to them that the killer bites the wives/mothers...