Tuberculosis

Three of the most important women in Poe's life died of tuberculosis. Although the "pestilence" in the story "Masque of the Red Death" is not defined, it seems reasonable to assume that it is inspired in some ways by Poe's experience with tuberculosis. The distinguishing mark of the "Red Death" is profuse bleeding, just as the distinguishing sign of tuberculosis is the coughing up of blood. According to Britannica Online, tuberculosis, often referred to in literature as "consumption," is "one of the great scourges of mankind." The disease "reached near-epic proportions" in industrializing urban areas in the eighteenth and nineteenth centuries. During this time, it was "the leading cause of death for all age groups in the Western world."

Impressionism

Much of Poe's writing can be referred to as "impressionist," depicting the subtle details of a sensitive mind from a highly subjective perspective. Britannica Online describes an...