"The Lake Isle of Innisfree" is written with an abab rhyme scheme corresponding to each of the three quatrains in the poem, which are defined as a stanza composed of four lines which may or may not have a set line length. Also prevalent is the use of alliteration and assonance, both of which emphasize the musical tone and rhythm of the piece.

When a stanza in a poem has a pattern of rhymes it is called a "rhyme scheme." "The Lake Isle of Innisfree" utilizes end rhyme in an abab rhyme scheme. This means that the end of the first line of a stanza rhymes with the end of the third line, and the end of the second line of a stanza rhymes with the end of the fourth line. All three of the quatrains in "The Lake Isle of Innisfree" display an abab rhyme scheme.

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