The settings of the stories range from the rural to the urban, although the majority have a small town or suburban setting that will not only be familiar to many readers, but also suggests that homosexuality is not urban or exotic, but a part of everyday life in every part of the United States. Jacqueline Woodson's story "Slipping Away" takes place at a summer beach colony, where questions of sexuality threaten to separate two best "summer friends." Francesca Lia Block's touching tale of a boyfriend and girlfriend whose relationship makes an important shift takes place in San Francisco.

Bruce Coville's story "Am I Blue?" takes place in a college town. There is as much variety in the settings as there is in the teens who inhabit them and in their questions about sexuality.