What does Virgil mean when he says Saul already disappeared? -When exactly did Saul “disappear”?

Virgil states that Saul is just running away and that he has already disappeared. "Feels like you are fucking running. " Saul really is a shell of his former self. He is like a ghost with no aim, no home, no identity, and no purpose.

Interesting question. What exactly does Virgil mean by saying Saul had already “disappeared,” and at what point in the story did Saul actually disappear?

Virgil means that Saul has already lost his sense of identity and purpose. He is like a ghost, running away without a home or direction, so Saul has “disappeared” emotionally before he physically leaves.