Long Day's Journey into Night was first adapted to film by Sidney Lumet, and starred Katharine Hepburn, Sir Ralph Richardson, Jason Robards, Jr., and Dean Stockwell. A black and white film, Embassy, 1962; available from Republic Pictures Home Video.

Long Day's Journey into Night was produced again as a made for television film by Jonathan Miller, using Sinclair Lewis's adaptation of the play, and starring Peter Gallagher, Jack Lemmon, Bethel Leslie, and Kevin Spacey, in 1988; available from Lorimar Home Video/Vestron.

A third version of the play, filmed at the Tom Patterson Theatre in Stratford, Ontario, Canada, was directed by David Wellington, and starred Peter Donaldson, Martha Henry, William Hutt, and Tom McCamus, Stratford Festival, 1996; not currently available.