Apollinaris's opinions aroused the opposition of the Cappadocian fathers and were condemned at the Council of Constantinople in 381, but his works circulated widely under the names of orthodox personalities, and as such they influenced profoundly the theology of Cyril of Alexandria (412–444). Cyril, however, was willing to admit at least the mystical reality of the two natures after the incarnation. His successor as patriarch of Alexandria, Dioscorus (444–451), less subtle and more impetuously ambitious for his see, made an uncompromising one-nature Christology the basis of his theology, and enunciated it in his vindication of the archimandrite Eutyches at the Second Council of Ephesus in August 449 (the "Robber Council"). The Council of Chalcedon reversed this situation, and Dioscorus himself was condemned (though for indiscipline rather than for heresy) and exiled. However, a large proportion of Eastern Christians, especially in Egypt, showed that they supported the one-nature Christology and rejected Chalcedon.
Dioscorus died in exile at Gangra in Paphlagonia in 454.
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