The Crying of Lot 49

What is the main conflict in The Crying of Lot 49 by Thomas Pynchon?

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Oedipa Maas is surprised to find that she has been named co-executor of the will of her former lover, real estate investor Pierce Inverarity. Her husband, Mucho Maas, an overly sensitive DJ, is not helpful, and neither is her psychiatrist, Dr. Hilarius, who calls her in the middle of the night and encourages her to participate in a study in which housewives take LSD.