What is the main conflict in The Corrections by Jonathan Franzen?

The Corrections by Jonathan Franzen, written in 2001, is an award-winning novel (2001 National Book Award and 2002 James Tait Black Memorial Prize). The story gives a comedic look at a Midwestern family and the tragic events that have plagued their lives. The three children of Enid and Alfred Lambert (Gary, Chip, and Denise) are simultaneously dealing with problems in their own lives largely as a result of bad choices. As Alfred suffers from Parkinson's disease, Enid desires to bring the family back together to celebrate Christmas at their home in St. Jude. Things go from bad to worse and force the family to face their problems.