Often used in shamanic rituals and for mind-alteration purposes, these substances grow extensively throughout the New World.
This location provides the earliest known evidence of a human history of mushroom use.
Round Head Period
This era likely started around the ninth millennium and ended before the seventh millennium B.C.E.
This is an ancient substance with psychedelic properties that no one yet has been able to identify.
This is a multipurpose plant with psychoactive properties whose fibers could be used in weaving.
This is possibly a source of addiction that is considered most socially acceptable and also inspired the slave trade to refine.
This substance is indicated as a major player in ending Medieval Times through its establishment of trade routes and connections to exotic locations.
This substance helped to increase demand for another addicting substance known as...
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