The following sections of this BookRags Literature Study Guide is offprint from Gale's For Students Series: Presenting Analysis, Context, and Criticism on Commonly Studied Works: Introduction, Author Biography, Plot Summary, Characters, Themes, Style, Historical Context, Critical Overview, Criticism and Critical Essays, Media Adaptations, Topics for Further Study, Compare & Contrast, What Do I Read Next?, For Further Study, and Sources.
(c)1998-2002; (c)2002 by Gale. Gale is an imprint of The Gale Group, Inc., a division of Thomson Learning, Inc. Gale and Design and Thomson Learning are trademarks used herein under license.
The following sections, if they exist, are offprint from Beacham's Encyclopedia of Popular Fiction: "Social Concerns", "Thematic Overview", "Techniques", "Literary Precedents", "Key Questions", "Related Titles", "Adaptations", "Related Web Sites". (c)1994-2005, by Walton Beacham.
The following sections, if they exist, are offprint from Beacham's Guide to Literature for Young Adults: "About the Author", "Overview", "Setting", "Literary Qualities", "Social Sensitivity", "Topics for Discussion", "Ideas for Reports and Papers". (c)1994-2005, by Walton Beacham.
All other sections in this Literature Study Guide are owned and copyrighted by BookRags, Inc.
Acetylcholine (ACh) is a major NEUROTRANSMITTER in the central and peripheral nervous systems. It is the ester of acetate and choline, formed by the enzyme choline acetyl transferase, from choline and acetyl-CoA. This was the first substance (ca. 1906) to meet the criteria of identification for a neurotransmitter. Later, acetylcholine was shown to be the general neurotransmitter for the neuromuscular junctions. In all vertebrate species, it is the major neurotransmitter for all autonomic ganglia and the neurotransmitter between parasympathetic ganglia and their target cells. Acetylcholine neurotransmission occurs widely within the central nervous system. Collections of NEURONS arising within the brain—the medulla, the pons, or the anterior diencephalon—innervate a wide set of cortical and subcortical targets; some of these circuits are destroyed in Alzheimer's disease.
COOPER, J. R., BLOOM, F. E., & ROTH, R. H. (1996). The biochemical basis of neuropharmacology, 7th ed. New York: Oxford University Press.