is he?’ Upon which his neighbour still was silent, but cast up his eyes and said something to himself; at which the first citizen turned pale, and said no more but this, ‘Then I am a dead man too’, and went home immediately and sent for a neighbouring apothecary to give him something preventive, for he had not yet found himself ill; but the apothecary, opening his breast, fetched a sigh, and said no more but this, ‘Look up to God’; and the man died in a few hours.

Now let any man judge from a case like this if it is possible for the regulations of magistrates, either by shutting up the sick or removing them, to stop an infection which spreads itself from man to man even while they are perfectly well and insensible of its approach, and may be so for many days.

It may be proper to ask here how long it may be supposed men might have the seeds of the contagion in them before it discovered itself in this fatal manner, and how long they might go about seemingly whole, and yet be contagious to all those that came near them.  I believe the most experienced physicians cannot answer this question directly any more than I can; and something an ordinary observer may take notice of, which may pass their observations.  The opinion of physicians abroad seems to be that it may lie dormant in the spirits or in the blood-vessels a very considerable time.  Why else do they exact a quarantine of those who came into their harbours and ports from suspected places?  Forty days is, one would think, too long for nature to struggle with such an enemy as this, and not conquer it or yield to it.  But I could not think, by my own observation, that they can be infected so as to be contagious to others above fifteen or sixteen days at furthest; and on that score it was, that when a house was shut up in the city and any one had died of the plague, but nobody appeared to be ill in the family for sixteen or eighteen days after, they were not so strict but that they would connive at their going privately abroad; nor would people be much afraid of them afterward, but rather think they were fortified the better, having not been vulnerable when the enemy was in their own house; but we sometimes found it had lain much longer concealed.

Upon the foot of all these observations I must say that though Providence seemed to direct my conduct to be otherwise, yet it is my opinion, and I must leave it as a prescription, viz., that the best physic against the plague is to run away from it.  I know people encourage themselves by saying God is able to keep us in the midst of danger, and able to overtake us when we think ourselves out of danger; and this kept thousands in the town whose carcases went into the great pits by cartloads, and who, if they had fled from the danger, had, I believe, been safe from the disaster; at least ’tis probable they had been safe.