are covered with a white sodden epidermis, and furnish a scanty but very infective discharge.  Under the influence of irritation and want of rest, as at the anus or at the angle of the mouth, they are apt to become fissured and superficially ulcerated, and the discharge then becomes abundant and may crust on the surface, forming yellow scabs.  At the angle of the mouth the condylomatous patches may spread to the cheek, and when they ulcerate may leave fissure-like scars radiating from the mouth—­an appearance best seen in inherited syphilis (Fig. 44).

The Appendages of the Skin.—­The hair loses its gloss, becomes dry and brittle, and readily falls out, either as an exaggeration of the normal shedding of the hair, or in scattered areas over the scalp (syphilitic alopoecia).  The hair is not re-formed in the scars which result from ulcerated lesions of the scalp.  The nail-folds occasionally present a pustular eruption and superficial ulceration, to which the name syphilitic onychia has been applied; more commonly the nails become brittle and ragged, and they may even be shed.

The Mucous Membranes, and especially those of the mouth and throat, suffer from lesions similar to those met with on the skin.  On a mucous surface the papular eruption assumes the form of mucous patches, which are areas with a congested base covered with a thin white film of sodden epithelium like wet tissue-paper.  They are best seen on the inner aspect of the cheeks, the soft palate, uvula, pillars of the fauces, and tonsils.  In addition to mucous patches, there may be a number of small, superficial, kidney-shaped ulcers, especially along the margins of the tongue and on the tonsils.  In the absence of mucous patches and ulcers, the sore throat may be characterised by a bluish tinge of the inflamed mucous membrane and a thin film of shed epithelium on the surface.  Sometimes there is an elongated sinuous film which has been likened to the track of a snail.  In the larynx the presence of congestion, oedema, and mucous patches may be the cause of persistent hoarseness.  The tongue often presents a combination of lesions, including ulcers, patches where the papillae are absent, fissures, and raised white papules resembling warts, especially towards the centre of the dorsum.  These lesions are specially apt to occur in those who smoke, drink undiluted alcohol or spirits, or eat hot condiments to excess, or who have irregular, sharp-cornered teeth.  At a later period, and in those who are broken down in health from intemperance or other cause, the sore throat may take the form of rapidly spreading, penetrating ulcers in the soft palate and pillars of the fauces, which may lead to extensive destruction of tissue, with subsequent scars and deformity highly characteristic of previous syphilis.

In the Bones, lesions occur which assume the clinical features of an evanescent periostitis, the patient complaining of nocturnal pains over the frontal bone, sternum, tibiae, and ulnae, and localised tenderness on tapping over these bones.