When the quantity of urine, or of excrement, distends the bladder, or rectum, those parts contract, and exclude their contents, and many other muscles by association act along with them; but if these evacuations are not soon complied with, pain is produced by a little further extension of the muscular fibres:  a similar pain is caused in the muscles, when a limb is much extended for the reduction of dislocated bones; and in the punishment of the rack:  and in the painful cramps of the calf of the leg, or of other muscles, for a greater degree of contraction of a muscle, than the movement of the two bones, to which its ends are affixed, will admit of, must give similar pain to that, which is produced by extending it beyond its due length.  And the pain from punctures or incisions arises from the distention of the fibres, as the knife passes through them; for it nearly ceases as soon as the division is completed.

All these motions of the muscles, that are thus naturally excited by the stimulus of distending bodies, are also liable to be called into strong action by their catenation, with the irritations or sensations produced by the momentum of the progressive particles of blood in the arteries, as in inflammatory fevers, or by acrid substances on other sensible organs, as in the strangury, or tenesmus, or cholera.

We shall conclude this account of the sense of extension by observing, that the want of its object is attended with a disagreeable sensation, as well as the excess of it.  In those hollow muscles, which have been accustomed to it, this disagreeable sensation is called faintness, emptiness, and sinking; and, when it arises to a certain degree, is attended with syncope, or a total quiescence of all motions, but the internal irritative ones, as happens from sudden loss of blood, or in the operation of tapping in the dropsy.

VIII. Of the Appetites of Hunger, Thirst, Heat, Extension, the want of fresh Air, animal Love, and the Suckling of Children.

Hunger is most probably perceived by those numerous ramifications of nerves that are seen about the upper opening of the stomach; and thirst by the nerves about the fauces, and the top of the gula.  The ideas of these senses are few in the generality of mankind, but are more numerous in those, who by disease, or indulgence, desire particular kinds of foods or liquids.

A sense of heat has already been spoken of, which may with propriety be called an appetite, as we painfully desire it, when it is deficient in quantity.

The sense of extension may be ranked amongst these appetites, since the deficiency of its object gives disagreeable sensation; when this happens in the arterial system, it is called faintness, and seems to bear some analogy to hunger and to cold; which like it are attended with emptiness of a part of the vascular system.