As the nerves of the senses have each their appropriated objects, which stimulate them into activity; so the muscular fibres, which are the terminations of other sets of nerves, have their peculiar objects, which excite them into action; the longitudinal muscles are stimulated into contraction by extension, whence the stretching or pandiculation after a long continued posture, during which they have been kept in a state of extension; and the hollow muscles are excited into action by distention, as those of the rectum and bladder are induced to protrude their contents from their sense of the distention rather than of the acrimony of those contents.

There are other objects adapted to stimulate the nerves, which terminate in variety of membranes, and those especially which form the terminations of canals; thus the preparations of mercury particularly affect the salivary glands, ipecacuanha the stomach, aloe the sphincter of the anus, cantharides that of the bladder, and lastly every gland of the body appears to be indued with a kind of taste, by which it selects or forms each its peculiar fluid from the blood; and by which it is irritated into activity.

Many of these external properties of bodies, which stimulate our organs of sense, do not seem to effect this by a single impulse, but by repeated impulses; as the nerve of the ear is probably not excitable by a single vibration of air, nor the optic nerve by a single particle of light; which circumstance produces some analogy between those two senses, at the same time the solidity of bodies is perceived by a single application of a solid body to the nerves of touch, and that even through the cuticle; and we are probably possessed of a peculiar sense to distinguish the nice degrees of heat and cold.

The senses of touch and of hearing acquaint us with the mechanical impact and vibration of bodies, those of smell and taste seem to acquaint us with some of their chemical properties, while the sense of vision and of heat acquaint us with the existence of their peculiar fluids.

Sensation and Volition.

II.  Many motions are produced by pleasure or pain, and that even in contradiction to the power of volition, as in laughing, or in the strangury; but as no name has been given to pleasure or pain, at the time it is exerted so as to cause fibrous motions, we have used the term sensation for this purpose; and mean it to bear the same analogy to pleasure and pain, that the word volition does to desire and aversion.

1.  It was mentioned in the fifth Section, that, what we have termed sensation is a motion of the central parts, or of the whole sensorium, beginning at some of the extremities of it.  This appears first, because our pains and pleasures are always caused by our ideas or muscular motions, which are the motions of the extremities of the sensorium.  And, secondly, because the sensation of pleasure or pain frequently continues some time after the ideas or muscular motions which excited it have ceased:  for we often feel a glow of pleasure from an agreeable reverie, for many minutes after the ideas, that were the subject of it, have escaped our memory; and frequently experience a dejection of spirits without being able to assign the cause of it but by much recollection.