Impatient of any longer delay, the conspirators came at length to the determination of putting the governor Hinojosa to death, and rising in a general insurrection. The principal ringleaders in this conspiracy were Don Sebastian de Castilla, Egas de Gusman, Basco Godinez, Balthazar Velasquez, and Gomez Hernandez, besides several other soldiers of note, most of whom were then resident in the city of La Plata. Having arranged their plan of operations, Don Sebastian and seven chosen accomplices went one morning to the residence of the governor, as soon as his gate was opened, to execute their vile purpose. The first person they met on entering the house was Alonzo de Castro, the deputy-governor, who questioned them on the reason of their present tumultuous appearance, as they seemed extremely agitated. They immediately put De Castro to death. Then forcing their way into the apartment of Hinojosa, they were astonished to find him gone: But after some search he was found in a retired corner, and dispatched.
After the death of Hinojosa, the conspirators went out to the market-place, proclaiming aloud, God save the king, the tyrant is dead! the common watchword in all the rebellions in Peru. Having collected all their associates, they seized on Pedro Hernandez Paniagua, the person employed by the late president Gasca to carry his letters to Gonzalo Pizarro, Juan Ortiz de Zarate, Antonio Alvarez, and all the wealthy citizens they could lay hold of. Martin de Robles, Paulo de Menezes, and Hondegardo the lawyer, against whom they were particularly incensed, made their escape. After this, they made proclamation by beat of drum, for all citizens and other inhabitants of La Plata, to repair immediately to the market-place and enrol themselves under their standard; on which Rodrigo de Ordlana, though then sheriff of the city, and many others, to the amount of a hundred and fifty-two persons, came forwards and inlisted, fearing for their lives in case of refusal. Don Sebastian was elected captain-general and chief-justice, and some days afterwards he got himself appointed mayor of the city: Gomez Hernandez a lawyer was appointed recorder; Hernando de Guillado and Garci Tello de Vega, were made captains; Juan de Huarte serjeant-major, Pedro de Castillo captain of artillery, Alvar Perez Payaz commissary-general, Diego Perez high sheriff, and Bartholomew de Santa Ana his deputy. Rodrigo de Orellana, and many of the citizens, who now joined the rebels, acted merely from fear of losing their lives if they refused or even hesitated, though loyal subjects in their hearts.