The Yazgulyam River is a tributary of the Panj (upper Oxus) Vanji district, southern Gorno-Badakhshan, Tajikistan. It flows in a narrow valley or gorge of some 100 kilometres northeast to southwest, roughly to . It lies between two high mountain ranges, the Vanj and the Yazgulami ranges. Settlements in the valley include Matraun, Bdyn, Anderbak and Dzhamak. The Yazgulyami inhabitants number about 4,000 (as of 1990, estimate for 1940 is about 2,000). In 1996 during the Tajik civil war, there was some fighting in Yazgulyam Gorge between Islamic Movement of Uzbekistan mujahidin and Tajik troops.
