|
translocator protein (18kDa)
|
|
| Identifiers | |
| Symbol | TSPO |
| Alt. Symbols | BZRP |
| Entrez | 706 |
| HUGO | 1158 |
| OMIM | 109610 |
| RefSeq | NM_007311 |
| UniProt | P30536 |
| Other data | |
| Locus | Chr. 22 q13.3 |
TSPO (Translocator Protein), also known as the peripheral benzodiazepine receptor (PBR), is a 18 kDa mitochondrial membrane protein.[1] Among its many functions are regulation of steroidogenesis and apoptosis.[2]
References
- ^ Papadopoulos V, Baraldi M, Guilarte TR, Knudsen TB, Lacapere JJ, Lindemann P, Norenberg MD, Nutt D, Weizman A, Zhang MR, Gavish M (2006). "Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function". Trends Pharmacol Sci 27 (8): 402-9. PMID 16822554.
- ^ Casellas P, Galiegue S, Basile AS (2002). "Peripheral benzodiazepine receptors and mitochondrial function". Neurochem Int 40 (6): 475-86. PMID 11850104.
