A silver bullet is a method to kill mythical creatures such as werewolves or a metaphor for any solution of extreme effectiveness. Silver Bullet may also refer to:
- Silver Bullet (film), a 1985 American film based on a Stephen King novella
- Silver Bullet (rapper), a British rapper remembered from his 1989 releases
- Silver Bullet (Knott's Berry Farm), a roller coaster at Knott's Berry Farm
- "Silver Bullet" (Hawthorne Heights song), a Hawthorne Heights song
- Silver Bullet (Coors Light train), the Coors Light train in the commercials
- Silver Bullet Band, see Bob Seger
- Silver Bullet (The Lone Ranger), ammunition used by The Lone Ranger
- 'Silver bullet', slang for a martini cocktail because it "is clear, potent and never misses its mark," however, this usage is on the decline
