Santiago is a fictional character in Anne Rice's The Vampire Chronicles series, specifically the novel Interview with the Vampire. Little history or background is given to this character in the novel; his role is primarily that of a European vampire who becomes an enemy of the main character, Louis de Pointe du Lac. After fleeing from their maker, Lestat de Lioncourt, the Creole vampires Louis and Claudia make their way to Europe to try and find other vampires and answers to the questions Lestat never answered. They make passage through a few countries before they decide to continue their search in Paris. It is in Paris that they make the first contact with another of their kind since they left Lestat, and that vampire is Santiago. Louis encounters Santiago while walking through the city one night. The character of Santiago was played by Stephen Rea in the 1994 film based on the novel.
