RTI may refer to:
- Radiodiffusion Television Ivoirienne - The state broadcaster of Ivory Coast
- Radio Taiwan International
- RTi, aka Matthew Cartwright, an electronica music artist.
- Reverse transcriptase inhibitor, a class of antiretroviral drug.
- Runtime infrastructure, the software that is required when implementing the computer simulation protocol: High Level Architecture (HLA).
- RunTime Interrupt, a type of low level interrupt on some types of computer architecture.
- Real-Time Innovations, a company that provides middleware infrastructure, tools, and services to develop real-time distributed systems.
- Research Triangle Institute, a not-for-profit organization performing research in many disciplines for government, industry and other clients throughout the United States and abroad.
- Right to Information Act, a law enacted by the Parliament of India giving access to government records.
- Ramp travel index - a measure of an off road vehicle articulation (ability to keep all wheels in contact with the ground over an uneven terrain.
- RTI International Metals, Inc. - one of the world's largest titanuium companies
- Road Traffic Information - the GPS navigation system in Volvo cars
- Response to intervention - Related to education; involves examining the performance of individuals after an educational intervention
- Reproductive tract infection - an infection that in women is considered to be nonfatal. If untreated, however, it may develop into a serious health problem such as Pelvic Inflammatory Disease, ectopic pregnancy, infertility, fetal loss, and cervical cancer.


