ROI or Roi may refer to:
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As an abbreviation
- Reactive oxygen intermediates, in Immunology (Biology)
- Region of interest, for example in image analysis or image processing
- Release of Information, in Health Information Management
- Republic of Ireland
- Republic of India
- Residue on ignition, in analytical chemistry
- Return on Investment, in accounting and finance
- Roma Civic Initiative (Romská občanská iniciativa), a Roma political party, based in Slovakia.
- Russian Olympiad in Informatics, an annual informatics competition for secondary school students in Russia
As a place name
- Roi-Namur, an island in the Marshall Islands
- Roi Et and Roi Et province in Thailand
As a person's name
- Antoine Rigaudeau, French basketball player, nicknamed "Le Roi" ("the King")
- Roi Klein, an Israeli Defense major
Miscellaneous
- a song by The Breeders
- USS Roi (CVE-103), a US war ship
Oratz Tool by Mr. Oratz to calculate work ROI.


