Project Genesis may refer to:
- Genesis class, a cruise ship.
- An alternate name for the TV-series Deepwater Black
- Project Genesis, a fictional technology from the Star Trek universe
- Toyota Project Genesis, a 1999 plan to attract more youthful buyers.
- Genesis (Final Fantasy character), a character in the Compilation of Final Fantasy VII.
- Project Genesis is an Orthodox Judaism website that teaches Judaism see torah.org
- Genesis Device is an LGPL engine
