A porcupine is a mammal best known for its coat of sharp spines, or quills, that provides a defense from predators. Porcupine may also refer to:
- Porcupine Tree, an English progressive rock band.
- Porcupine, South Dakota
- Porcupine Mountains, Michigan
- Porcupine (album) by Echo & the Bunnymen
- Porcupine (comics) the fictional Marvel Comics character
- Porcupine River a River with its source in the Yukon and flows through Alaska
- Members of the Free State Project are often referred to as porcupines or Porcs.
