Monopole may refer to:
- Magnetic monopole, or Dirac monopole, a hypothetical particle that may be loosely described as a magnet with only one pole
- Wu-Yang monopole, a monopole solution of Yang-Mills equations
- 't Hooft-Polyakov monopole, analogous to Dirac monopole, but without singularities
- Seiberg-Witten monopole, a solution of the Seiberg-Witten equations
- Monopole (mathematics), a connection over a principal bundle G with a section (the Higgs field) of the associated adjoint bundle
- Monopole (wine), an appellation owned by only one winery
- Monopole antenna, a radio antenna that replaces half of a dipole antenna with a ground plane at right-angles to the remaining half
- A monopole, a common term for a tubular self-supporting telecommunications mast, especially as distinguished from a lattice tower or pylon
