Mississippi Delta may refer to:
- Mississippi Delta, a distinct cultural area in northwest Mississippi state; part of the Mississippi embayment
- Mississippi River Delta, a landform at the mouth of the Mississippi River formed by sediment deposits
- Mississippi embayment, the northern part of the Mississippi alluvial plain, between central Louisiana and southern Illinois
- Mississippi Alluvial Plain, the entire alluvial plain of the Mississippi River, from the river mouth to southern Illinois
