Mendel is a surname, and may refer to:
- Gregor Mendel (1822–1884), often called the "father of Genetics"
- Arthur Mendel, US musicologist
- Lafayette Mendel, American biochemist
- August Neander, German theologian (born David Mendel)
- Barry Mendel, American film producer
- Nate Mendel, American musician
- Menachem Mendel (disambiguation), several people with this name
- Mendel (Hungarian family), a prominent Hungarian family that flourished in the 15th century
