Macho can refer to:
- overtly masculine, from the Spanish word Machismo
- Massive compact halo object (MACHO), a general name for any kind of astronomical body that might explain the apparent presence of dark matter in galaxy halos.
- Macho (band), a short-lived disco group in the late 1970s.
- Machos, a community in western Ilia in Greece.
- Macho, swahili word for eyes.
