Glycerate 3-phosphate

Glycerate 3-phosphate
Systematic (IUPAC) name
(2R)-2-hydroxy-3-phosphonooxy-propanoate
Identifiers
CAS number	820-11-1
PubChem	439183
Chemical data
Formula	C3H7O7P
Molar mass	186.058
Complete data

Glycerate 3-phosphate (GP) or 3-phosphoglycerate (3PG) is a biochemically significant 3-carbon molecule that is a metabolic intermediate in both glycolysis and the Calvin cycle. This chemical is often termed PGA when referring to the Calvin cycle. 3-phosphoglycerate is the resultant of the split of 6 carbon intermediate that is so unstable it splits instantly. And two 3-phosphoglycerate is produced for each molecule of CO₂.

Glycolysis

1,3-bisphospho-D-glycerate	3-phosphoglycerate kinase		3-phospho-D-glycerate	Phosphoglyceromutase		2-phospho-D-glycerate
	ADP	ATP
	ADP	ATP
	3-phosphoglycerate kinase			Phosphoglyceromutase

Compound C00236 at KEGG Pathway Database. Enzyme 2.7.2.3 at KEGG Pathway Database. Compound C00197 at KEGG Pathway Database. Enzyme 5.4.2.1 at KEGG Pathway Database. Compound C00631 at KEGG Pathway Database.

Calvin cycle

In the Calvin cycle, two glycerate 3-phosphate molecules are reduced to form two molecules of glyceraldehyde 3-phosphate (PGAL). This is the first compound formed during the C3 or Calvin cycle. It is a reactive biomolecule which is easily reduced.

Amino acid synthesis

Glycerate 3-phosphate is also a precursor for serine, which in turn, can create cysteine and glycine through the homocysteine cycle.

See also

•  • e  Glycolysis Metabolic Pathway

Glucose Hexokinase Glucose-6-phosphate Phosphoglucoisomerase Fructose 6-phosphate Phosphofructokinase Fructose 1,6-bisphosphate Fructose bisphosphate aldolase Dihydroxyacetone phosphate Glyceraldehyde 3-phosphate Triosephosphate isomerase Glyceraldehyde 3-phosphate Glyceraldehyde phosphate dehydrogenase ATP ADP ATP ADP NAD+ + Pi NADH + H+ + 2 NAD+ + Pi NADH + H+ 1,3-Bisphosphoglycerate Phosphoglycerate kinase 3-Phosphoglycerate Phosphoglycerate mutase 2-Phosphoglycerate Enolase Phosphoenolpyruvate Pyruvate kinase Pyruvate Pyruvate dehydrogenase Acetyl-CoA ADP ATP H2O ADP ATP CoA + NAD+ NADH + H+ + CO2 2 2 2 2 2 2 ADP ATP H2O

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