Chemotherapy regimens
About 2 pages (680 words)
Chemotherapy regimens are often identified with acronyms, identifying the agents used in combination. Unfortunately, the letters used are not consistent across regimens, and in some cases (for example, "BEACOPP") the same letter is used to represent two different treatments. Because of this, there is not a naming standard for chemotherapy regimens, and this page merely represents commonly used conventions. The term "Induction regimens" refers to a chemotherapy regimen which is used for the initial treatment of a disease.
Name
Components
Example of uses, and other notes
ABVD Adriamycin , bleomycin , vinblastine , dacarbazine Hodgkin's lymphoma
AC Adriamycin /Doxorubicin , Cyclophosphamide Breast cancer
BEACOPP Bleomycin , etoposide , Adriamycin (doxorubicin ), cyclophosphamide , Oncovin (vincristine ), procarbazine , prednisone Hodgkin's lymphoma
BEP Bleomycin , etoposide , platinum (cisplatin )Testicular cancer , germ cell tumors
CAF Cyclophosphamide , Adriamycin /Doxorubicin , 5-FU /Fluorouracil Breast cancer
CAV Cyclophosphamide , Adriamycin /Doxorubicin , Vincristine Lung cancer
CBV Cyclophosphamide , BCNU (Carmustine) , VP-16 (etoposide) Lymphoma
CHOP Cyclophosphamide , doxorubicin (hydroxydoxorubicin ), vincristine (Oncovin ), prednisone Non-Hodgkin lymphoma
CHOP-R R-CHOP CHOP + rituximab
B cell non-Hodgkin lymphoma
COP CVP Cyclophosphamide , vincristine (Oncovin), and prednisone Non-Hodgkin lymphoma in patients with history of cardiovascular disease
CMF Cyclophosphamide , Methotrexate , and 5-Fluorouracil Breast Cancer
COPP Cyclophosphamide , Oncovin (vincristine), procarbazine and prednisoneNon-Hodgkin lymphoma
EC Epirubicin , Cyclophosphamide Breast cancer
ECF Epirubicin , cisplatin , fluorouracil Gastric cancer and oesophageal cancer
FOLFOX Fluorouracil , leucovorin (folinic acid ), and oxaliplatin Colorectal cancer
m-BACOD Methotrexate , bleomycin , doxorubicin (Adriamycin), cyclophosphamide, vincristine (Oncovin), dexamethasone (Decadron )Non-Hodgkin lymphoma
MACOP-B Methotrexate , leucovorin , doxorubicin (Adriamycin), cyclophosphamide , vincristine (Oncovin), prednisone , bleomycin Non-Hodgkin lymphoma
MOPP Mechlorethamine , vincristine (oncovin ), procarbazine , prednisone Hodgkin's lymphoma
PCV Procarbazine , lomustine (CCNU), vincristine Brain tumors
ProMACE-MOPP Methotrexate , doxorubicin (Adriamycin), cyclophosphamide , etoposide + MOPP Non-Hodgkin lymphoma
ProMACE-CytaBOM Prednisone , doxorubicin (adriamycin ), cyclophosphamide , etoposide , cytarabine , bleomycin , vincristine (Oncovin), methotrexate , leucovorin Non-Hodgkin lymphoma
R-FCM Rituximab , fludarabine , cyclophosphamide , mitoxantrone B cell non-Hodgkin lymphoma
Stanford V Doxorubicin (Adriamycin ), mechlorethamine , bleomycin , vinblastine, vincristine (Oncovin), etoposide (VP-16 ), prednisoneHodgkin's lymphoma
Thal/Dex Thalidomide , dexamethasoneMultiple myeloma
VAD Vincristine , Adriamycin (doxorubicin), dexamethasone Multiple myeloma
See also
External links
Chemotherapeutic agents/Antineoplastic agents (L01 )
Alkylating and alkylating-like agents Nitrogen mustards :Chlorambucil , Chlormethine , Cyclophosphamide , Ifosfamide , Melphalan ). Nitrosoureas :Carmustine , Fotemustine , Lomustine , Streptozocin ). Platinum (alkylating-like):Carboplatin , Cisplatin , Oxaliplatin , BBR3464 ). Busulfan , Dacarbazine , Procarbazine , Temozolomide , ThioTEPA , Uramustine
Antimetabolites Folic acid :Aminopterin , Methotrexate , Pemetrexed , Raltitrexed ). Purine :Cladribine , Clofarabine , Fludarabine , Mercaptopurine , Pentostatin , Thioguanine ). Pyrimidine :Capecitabine , Cytarabine , Fluorouracil , Floxuridine , Gemcitabine )
Spindle poison /mitotic inhibitor Taxane :Docetaxel , Paclitaxel ). Vinca :Vinblastine , Vincristine , Vindesine , Vinorelbine ).
Cytotoxic/antitumor antibiotics Anthracycline family :Daunorubicin , Doxorubicin , Epirubicin , Idarubicin , Mitoxantrone , Valrubicin ) - streptomyces Actinomycin , Bleomycin , Mitomycin , Plicamycin ) - Hydroxyurea
Topoisomerase inhibitors Camptotheca :Camptothecin , Topotecan , Irinotecan ), Podophyllum :Etoposide , Teniposide )
CI monoclonal antibodies Receptor tyrosine kinase Cetuximab , Panitumumab , Trastuzumab ) - CD20 Rituximab , Tositumomab ) - other (Alemtuzumab , Bevacizumab , Gemtuzumab )
Photosensitizers Aminolevulinic acid , Methyl aminolevulinate , Porfimer sodium , Verteporfin
Tyrosine kinase inhibitors Dasatinib , Erlotinib , Gefitinib , Imatinib , Lapatinib , Nilotinib , Sorafenib , Sunitinib
Other
retinoids Alitretinoin , Tretinoin ) - Altretamine , Amsacrine , Anagrelide , Arsenic trioxide , Asparaginase (Pegaspargase ), Bexarotene , Bortezomib , Denileukin diftitox , Estramustine , Ixabepilone , Masoprocol , Mitotane
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