Callirhoe or Callirrhoe may mean:
- Callirhoe (genus), a genus of plant within the Mallow family
- Callirrhoe (moon), a moon of Jupiter
Callirhoe or Callirrhoe is the name of several women from Greek mythology:
- Callirhoê, daughter of Lycus, who betrayed her father to her lover, Diomedes.
- Callirrhoe (naiad), a daughter of Oceanus and mother of Echidna, one of the Oceanids
- Callirhoe, the daughter of the river-god Achelous, who betrothed her to Alcmaeon
- Callirhoe, a woman of Calydon who scorned, Coresus, a priest of Dionysus who in turn threatened to inflict all the women of Calydon with a plague that led to insanity (see Bacchae). In the end Coresus sacrificed himself to save her from being sacrificed. Callirhoe, in remorse, cut her throat.
- Callirhoe, daughter of the river-god Scamander and the nymph Idaea. She had four children by Tros: Cleopatra, Ilus, Assaracus, and Ganymedes. Other sources say that Tros was instead her son by Erichthonius.
- Callirhoe, wife of Piras, son of king Argus of Argos
- Callirhoe, one of the three naiads who are the mothers of the Tyrian race. They were joined to the sons of the soil.
Nonn.40.535ff. Callirhoe may also be:
- Callirhoe, the heroine of the only novel known to have been written by the ancient Greek author Chariton
- Callirhoé, the only ballet written by French composer Cécile Chaminade
- Callirhoe, the name of the waters Herod the Great sought as relief from his terminal illness, said to be east of the Dead Sea
