| Brunner's glands | |
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| Section of duodenum of cat. (Duodenal glands in submucosa labeled at right, fourth from the top.) | |
| Latin | glandulae duodenales |
| Gray's | subject #248 1176 |
| Dorlands/Elsevier | g_06/12392383 |
Brunner's glands (or duodenal glands) are compound tubular submucosal glands located throughout the duodenum. The main function of these glands is to produce an alkaline secretion (containing bicarbonate) in order to:
- protect the duodenum from the acidic content of chyme (which is introduced into the duodenum from the stomach);
- provide an alkaline condition for the intestinal enzymes to be active, thus enabling absorption to take place;
- lubricate the intestinal walls.
They are also the distinguishing feature of the duodenum.
Human brunner's gland
External links
- duodenal+glands at eMedicine Dictionary
- Histology at BU 11504loa - "Digestive System: Alimentary Canal: pyloro/duodenal junction, duodenum"
- Histology at BU 11513loa - "Digestive System: Alimentary Canal: pyloro/duodenal junction"
- Histology at BU 11609loa - "Digestive System: Alimentary Canal: duodenum, plicae circularis"
- Histology at OU 52_06
- Histology at USC gi/c_36
- Histology at USC gi/c_39
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| Enteric nervous system | Meissner's plexus - Auerbach's plexus |
| Exocrine | Chief cells (Pepsinogen) - Parietal cells (Gastric acid, Intrinsic factor) - Goblet cells (Mucus) |
| Endocrine/paracrine | G cells (gastrin), D cells (somatostatin) - ECL cells (Histamine) - enterogastrone: I cells (CCK), K cells (GIP), S cells (secretin) |
| Border | Brunner's glands - Paneth cells - Enterocytes |
| Fluids | Saliva - Bile - Intestinal juice - Gastric juice - Pancreatic juice |
| Processes | Swallowing - Vomiting - Peristalsis (Interstitial cell of Cajal) - Migrating motor complex - Borborygmus - Gastrocolic reflex - Segmentation contractions - Defecation |
