ALICE may stand for:
- A Large Ion Collider Experiment, a high energy heavy ion- and particle physics experiment at the European Center for Nuclear Research CERN's Large Hadron Collider LHC
- All-purpose Lightweight Individual Carrying Equipment, a package of load-bearing equipment utilized by the United States Armed Forces. Has mostly been replaced by MOLLE systems.
- Artificial Linguistic Internet Computer Entity, a natural language processing chatterbot
- Advanced Logistic & Inconsequence Cognizing Equipment, an advanced sentient artificial intelligence featured in the Gundam Sentinel novel.
