Dictionary of Biological Psychology
(ME) Chronic muscular PAIN and FATIGUE supposedly associated with an inflammatory process in BRAIN and/or SPINAL CORD. Evidence for organic pathology has been widely accepted by legislative bodies, the law courts and patient support groups but scientific support is unconvincing.
Neurological studies (see Thomas, 1993) have instead indicated central subjective fatigue after minimal exertion without verifiable evidence of inflammatory immunological (see IMMUNE SYSTEM) or degenerative change. The condition is more accurately subsumed as CHRONIC FATIGUE SYNDROME but is associated with many other distressing symptoms especially—in over 75% of cases—DEPRESSION and ANXIETY and it presents a serious clinical challenge.
Reference
Thomas P.K. (1993) The chronic fatigue syndrome: what do we know? British Medical Journal 306:1557–1558.
L.JACOB HERBERG
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