Dictionary of Biological Psychology
An agonist at dopamine receptors, with preference for D2 over D1 dopamine receptors (see D1–D5 DOPAMINE RECEPTORS).
It has been widely used in psychopharmacological studies as a drug capable of stimulating dopamine receptors, and its effects are often contrasted with those of AMPHETAMINE, which promotes release of dopamine rather than directly stimulating receptors (see, for example, ROTATION). It is a derivative of MORPHINE and, like morphine, induces nausea and vomiting in humans (but not rodents, which do not vomit). It is therapeutically used as an emetic (see EMESIS) in cases of poisoning.
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