In 1957, Twelve Angry Men was made into a film starring Henry Fonda and Lee J. Cobb and directed by Sydney Lumet, with a screenplay by Rose (produced by Orion-Nova Productions/United Artists). It is available on DVD through MGM/UA Video.

In 1997, the cable channel Showtime released the made-for-television movie of Twelve Angry Men, directed by William Friedkin and starring Jack Lemmon as Juror Eight, with George C. Scott, Hume Cronyn, James Gandolfini, and Tony Danza. Rose produced an updated screenplay for this production. The videotape, put out by MGM/UA Video, has limited availability.