Paradise Lost has never been adapted as a film or play. However, it is discussed in the video Milton and 17th-century Poetry (Films for the Humanities and Sciences, Princeton N.J.).

The story of the garden of Eden is included in the film The Bible—In the Beginning (1966), directed by John Huston and produced by Dino DeLaurentis, starring Ulla Bergryd as Eve and Michael Parks as Adam.

The devil's work is presented in four periods, one of which is the temptation of Adam and Eve in Eden, in Luigi Maggi's film Satan—or the Drama of Humanity (1912).

There is a reference to Paradise Lost in the 1967 Star Trek episode "Space Seed." Ricardo Montalban portrays Kahn (who resurfaces in the movie Star Trek II: The Wrath of Kahn), a eugenically enhanced human who flees earth after leading an unsuccessful revolt of "supermen" like himself. Having taken...