Director Robert Siodmak's 1946 film The Killers is the first adaptation of Hemingway's story for the screen. It stars Burt Lancaster, Ava Gardner, and Edmond O'Brien and is available at most video stores and many libraries.

Director Donald Siegel's 1964 film The Killers also adapts Hemingway's story. Siegel's version stars Lee Marvin, Clu Gulager, John Cassavetes, Angie Dickinson, and Ronald Reagan and is available at most video stores and many libraries.