Lewis's Arrowsmith (1925) is one of his most admired novels. It portrays the career of Martin Arrowsmith, a dedicated, idealistic physician and truth-seeker who is severely tested by the cynicism he encounters in the medical profession.
The Damnation of Theron Ware (1896), by Harold Frederic, has many similarities to Elmer Gantry. The Reverend Theron Ware is a young, ambitious Methodist minister whose encounter with the new intellectual ideas of "higher criticism" and Darwinism destroys his simple faith in Methodism and ruins his career.
Thornton Wilder's novel Heaven Is My Destination (1934), which is both comic and sad,.....
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