In the Cardinal's palace, Pescara and a doctor are discussing Ferdinand, who the doctor says is suffering from the belief that he is a werewolf; Ferdinand has been found roaming the streets with dead body parts he has dug up out of graves. The doctor says Ferdinand is doing better after his treatment, but that he may relapse.
Ferdinand, the Cardinal, Malateste, and Bosola enter. Ferdinand demands to be left alone, then attacks his own shadow and talks nonsense. The doctor attempts to scare Ferdinand out of his crazy behavior, but Ferdinand rants and runs off. Pescara asks the Cardinal whether he knows why his brother has gone insane. The Cardinal admits in an aside that he must lie; he tells them a tale about Ferdinand seeing a ghost that reputedly appears.....
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