Folks are, at their heart, selfish, and anything they tell you is more often than not designed to meet their own goals. I know, because I ain't any different.”
-- Jane (Prologue)

Importance: This is one of Jane's first statements and it could be a sign that she is a less-than-honorable narrator, willing to say whatever she feels is necessary to reach her goals. However, Jane really has no goals as far as her narration to the reader goes, and her willingness to say that she is selfish will probably make her a more reliable narrator in the eyes of most readers.

There ain't nothing worth seeing in Nicodemus. It's just as cursed as Summerland, the same old evils prettied up with whitewash.”
-- Jackson (chapter 1)

Importance: This is a foreshadowing of the terrors Jane and Katherine will face once they reach Nicodemus. Jackson dies before they reach Nicodemus and Jane promises to take care of Lily.

But...
-- Katherine (chapter 4)