A Death in the Family was adapted to the stage as the play All the Way Home in 1960; a film version of the play was made in 1963.

On March 25, 2002, PBS broadcast an adaptation of A Death in the Family directed by Gil Cates and starring Annabeth Gish and James Cromwell, as part of its Masterpiece Theatre series. It was written by Robert W. Lenski. The series was later released on VHS from Public Broadcasting System.