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Sickle Cell Anemia | Research & Encyclopedia Articles

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Sickle-cell disease Summary

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Sickle Cell Anemia

Definition

Sickle cell anemia is an inherited blood disorder in which the body produces c-shaped red blood cells. Because of their shape, these cells may stick to each other or to the sides of blood vessels, and cause serious health disorders.

Description

Blood is made up of many kinds of cells, including red blood cells (RBCs). An important function of RBCs is to carry oxygen from the lungs to cells throughout the body. Red blood cells contain a molecule known as hemoglobin (pronounced HEE-muh-GLOW-bihn) that collects oxygen from the lungs then releases it when the RBC reaches other cells in the body.

Normally, red blood cells have a plump doughnut shape. In some cases, however, a person's body makes red blood cells that are curved with sharp points at the end. They are called sickle cells because they look like a sickle (a long farm tool with a curved blade that is used to cut grain).

Hemoglobin Genes

Sickle cell anemia is caused by defective genes. Genes are chemical units found in all cells that tell cells what functions to perform. For example, RBCs contain genes that tell the cell how to make hemoglobin molecules.

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Sickle Cell Anemia from UXL Complete Health Resource. ©2005-2006 by U•X•L. U•X•L is an imprint of Thomson Gale, a division of Thomson Learning, Inc. All rights reserved.

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