The following sections of this BookRags Literature Study Guide is offprint from Gale's For Students Series: Presenting Analysis, Context, and Criticism on Commonly Studied Works: Introduction, Author Biography, Plot Summary, Characters, Themes, Style, Historical Context, Critical Overview, Criticism and Critical Essays, Media Adaptations, Topics for Further Study, Compare & Contrast, What Do I Read Next?, For Further Study, and Sources.
(c)1998-2002; (c)2002 by Gale. Gale is an imprint of The Gale Group, Inc., a division of Thomson Learning, Inc. Gale and Design and Thomson Learning are trademarks used herein under license.
The following sections, if they exist, are offprint from Beacham's Encyclopedia of Popular Fiction: "Social Concerns", "Thematic Overview", "Techniques", "Literary Precedents", "Key Questions", "Related Titles", "Adaptations", "Related Web Sites". (c)1994-2005, by Walton Beacham.
The following sections, if they exist, are offprint from Beacham's Guide to Literature for Young Adults: "About the Author", "Overview", "Setting", "Literary Qualities", "Social Sensitivity", "Topics for Discussion", "Ideas for Reports and Papers". (c)1994-2005, by Walton Beacham.
All other sections in this Literature Study Guide are owned and copyrighted by BookRags, Inc.
Intact cells are comprised of a nucleus and cytoplasm. A nuclear envelope encloses chromatin, the nucleolus, and a matrix which fills the remaining space. The chromatin consists primarily of the genetic material DNA and histone proteins. The nucleolus is a small structure within the nucleus which is rich in ribosomal RNA and proteins. Nucleoli are associated with protein synthesis and enlarged nucleoli are observed in rapidly growing embryonic tissue (other than cleavage nuclei), cells actively engaged in protein synthesis, and malignant cells. The nuclear matrix contains mainly proteins.
The genetic instructions for an organism are encoded in nuclear DNA. Hence, when genetic replicates are desired, they are cloned by nuclear transplantation. Frogs were the first creatures produced by cloning and this was accomplished in Philadelphia in 1952. More recently, sheep (Dolly) and other creatures have been produced by cloning nuclei from adult animal donors. The cloning procedures for frogs or mammals consists of insertion of a nucleus into an egg that has been deprived of its own genetic material. The reconstituted egg, with a new nucleus, develops in accordance with the genetic instructions of the nuclear donor.
There are, of course, cells which do not contain the usual nuclear structures. Embryonic cleavage nuclei (cells forming a blastula) do not have a nucleolus. Obviously, they have the genetic competence to produce nucleoli when needed because gastrula and all later cells contain nucleoli. Mature red blood cells, erythrocytes, in most mammals have lost their nuclei. Nuclear loss does not preclude the competence to carry oxygen.