Growth Disorders - Research Article from Macmillan Science Library: Genetics

This encyclopedia article consists of approximately 5 pages of information about Growth Disorders.
This section contains 1,458 words
(approx. 5 pages at 300 words per page)
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Growth Disorders

Growth, which usually refers to skeletal growth since it determines final adult height, is an extremely complex process. As such, it is susceptible to a wide range of genetic and physiologic disturbances. Indeed, growth is adversely affected by many if not most chronic diseases of childhood, through many different mechanisms.

Skeletal growth depends on hormonal signals for regulation. It also requires the production of adequate amounts of cartilage, because most bone forms within a model or template made from cartilage. Primary disorders of growth, that is, disorders in which growth is intrinsically affected, therefore fall into two major categories: disorders of the endocrine (hormone) system and disorders of the growing skeleton itself (skeletal dysplasias). Many of the former and most of the latter are genetic disorders.

Endocrine Disorders

Growth hormone (GH) is produced by the pituitary gland at the base of the brain and is a...

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This section contains 1,458 words
(approx. 5 pages at 300 words per page)
Buy the Growth Disorders Encyclopedia Article
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Growth Disorders from Macmillan. Copyright © 2001-2006 by Macmillan Reference USA, an imprint of the Gale Group. All rights reserved.
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