The potential use of the microgravity environment for inroads in cancer research is both important and promising. Research opportunities are broad and will include many areas of examination for investigators who are trained in both basic and clinical sciences. As one example, studies have shown that mammalian cell culture conducted in a manner that does not allow cell settling as a result of gravitational forces holds promise in the propagation of three-dimensional tissue cellular arrays much like those that normally comprise tissue specimens in the intact body. The space shuttle and the International Space Station have only a minute fraction of the gravitational force present on Earth. Culture of tissues with a three-dimensional architecture on these research platforms provides a unique and powerful opportunity for studies of anti-cancer drug action with a more complex and natural tissue ultrastructure than can be attained in terrestrial laboratories.

NASA's...